Joyce Carlson
Papers
1
Total Citations
10
H-Index
1
About
Joyce Carlson’s research centers on clinical mass spectrometry and the development of robust, high-throughput methods for analyzing metabolic biomarkers, with a particular focus on vitamin B12 status. Her most cited work, “Semi-automated quantification of methylmalonic acid in human serum by LC-MS/MS” (2012, 10 citations), addresses a critical bottleneck in clinical diagnostics: the labor-intensive manual extraction and derivatization steps traditionally required for measuring methylmalonic acid (MMA), a sensitive biomarker of functional vitamin B12 deficiency. By introducing a semi-automated liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach, Carlson significantly improved workflow efficiency and reproducibility, making routine MMA quantification more accessible for clinical laboratories. This contribution is especially valuable given the growing recognition of B12 deficiency’s role in neurological and hematological disorders. While her citation count is modest, the practical impact of her work is substantial—her method has been adopted and referenced by other researchers seeking to streamline vitamin B12 assessment. Carlson’s dedication to refining analytical techniques underscores her commitment to translating complex laboratory science into tangible improvements in patient care.
Research Focus
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Top Papers
- 1