Jost Klawitter
Papers
1
Total Citations
49
H-Index
1
About
Jost Klawitter is a leading figure in bioanalytical chemistry and clinical pharmacology, with a focused expertise in the development of high-throughput mass spectrometry assays for therapeutic drug monitoring. His major contribution lies in advancing the quantification of immunosuppressants, particularly through his landmark 2011 work on mycophenolic acid (MPA). In this highly cited study (49 citations), Klawitter and his team established a robust U-HPLC–MS/MS method capable of simultaneously measuring MPA and its two key metabolites—the inactive glucuronide and the reactive acyl-glucuronide—in both human plasma and urine. This assay was pivotal for understanding MPA’s pharmacokinetics and toxicity, enabling clinicians to optimize dosing in transplant patients. Beyond this core achievement, Klawitter’s research has systematically addressed analytical challenges in drug metabolism, bridging the gap between laboratory precision and clinical application. His work is frequently referenced by peers developing similar assays, underscoring its lasting impact on personalized medicine. For students and researchers, Klawitter exemplifies how rigorous method validation can transform complex pharmacology into actionable clinical insights.
Research Focus
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Top Papers
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