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About

John P. Neoptolemos is a world-renowned pancreatic surgeon and translational researcher whose work has fundamentally reshaped the management of pancreatic diseases. His primary research areas span pancreatic cancer surgery, chronic pancreatitis genetics, and the standardization of complex pancreatic procedures. A landmark contribution is his discovery that cystic fibrosis carriers face a significantly increased risk of idiopathic chronic pancreatitis (114 citations), establishing a critical genetic link between CFTR mutations and pancreatic inflammation. As a leader in the International Study Group of Pancreatic Surgery, he co-authored expert consensus guidelines on distal pancreatectomy (73 citations), providing essential benchmarks for surgical safety and quality. More recently, he has pioneered complexity grading systems for minimally invasive pancreatoduodenectomy (17 citations), enabling safer patient selection and training for robotic and laparoscopic approaches. His comprehensive review on the evolution of oncosurgical management for pancreatic cancer (6 citations) distills decades of progress in multidisciplinary care. With a career spanning over 500 publications and countless international collaborations, Neoptolemos remains a pivotal figure in advancing both the science and practice of pancreatic surgery, directly improving outcomes for patients worldwide.