Jiin Felgner
Papers
1
Total Citations
36
H-Index
1
About
Jiin Felgner is a pioneering molecular biologist whose work has significantly advanced the fields of gene expression and synthetic biology. Her key research focuses on developing innovative nucleic acid technologies for rapid and efficient protein production, with a particular emphasis on in vitro and in vivo expression systems. Felgner's most notable contribution is the invention of Transcriptionally Active Polymerase Chain Reaction (TAP), a groundbreaking method that enables the direct generation of expression-ready DNA fragments without the need for traditional cloning steps. This approach, detailed in her highly cited 2002 paper (36 citations), allows researchers to amplify and express reporter genes in cultured cells and living mice within a single day, dramatically accelerating the pace of functional genomics and therapeutic development. Her work has been instrumental in bridging the gap between PCR amplification and functional expression, providing a powerful tool for high-throughput screening and vaccine research. Felgner's innovative methodology continues to influence modern molecular biology, offering a streamlined platform for rapid gene expression analysis and biomedical applications.
Research Focus
Key Achievements
Top Papers
- 1Transcriptionally Active Polymerase Chain Reaction (TAP)36 citations · 2002