Jeroen A. F. Boogers
Papers
1
Total Citations
120
H-Index
1
About
Jeroen A. F. Boogers is a leading figure in asymmetric catalysis, with a primary focus on developing highly efficient and selective methods for carbon-carbon bond formation. His most impactful work centers on the rhodium-catalyzed asymmetric conjugate addition of organoboron reagents to enones, a cornerstone reaction in organic synthesis. In his highly cited 2004 study (120 citations), Boogers pioneered the use of monodentate phosphoramidite ligands to enable the highly enantioselective addition of potassium organotrifluoroborates—a stable and versatile boron source—to various enones. Crucially, this breakthrough was achieved under anhydrous conditions, overcoming a major limitation of prior methods. By systematically employing high-throughput screening to optimize the catalyst, he demonstrated a powerful, practical approach for accessing chiral building blocks. This work has had a lasting impact on the field, providing chemists with a robust tool for asymmetric synthesis and inspiring further innovations in ligand design and organometallic catalysis. His contributions remain essential reading for researchers exploring enantioselective methodologies.
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