Jan Hannemann
Papers
1
Total Citations
547
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1
About
Jan Hannemann is a pioneering figure in plant systems biology, best known for developing high-throughput methodologies to dissect central carbon and nitrogen metabolism. His most influential work introduced a robot-based platform capable of measuring the activities of 23 key enzymes in *Arabidopsis thaliana* simultaneously, using optimized stopped assays coupled with enzyme cycling assays. This breakthrough, detailed in his 2004 paper (cited over 540 times), enabled researchers to systematically compare enzyme activity with transcript levels under dynamic conditions, such as diurnal cycles and prolonged darkness. By revealing the frequent disconnect between gene expression and metabolic flux, Hannemann’s platform became an essential tool for understanding plant metabolic regulation and stress responses. His contributions have profoundly shaped how scientists integrate enzymatic data with transcriptomics, providing a robust foundation for systems-level studies of plant physiology and bioenergy research.
Research Focus
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