James P. Carson
Papers
1
Total Citations
13
H-Index
1
About
James P. Carson is a leading computational neurobiologist whose research bridges genomics, neuroscience, and bioinformatics to map the molecular architecture of the developing brain. His most-cited work, "A Digital Atlas of Ion Channel Expression Patterns in the Two-Week-Old Rat Brain" (2014, 13 citations), established a foundational resource by systematically profiling the expression of 320 ion channels in the P14 rat brain using robotic in situ hybridization. This atlas provides an unprecedented, high-resolution view of how ion channels—critical for neuronal excitability and signaling—are distributed across brain regions during a key developmental window. Carson’s contributions include developing optimized methods for large-scale gene expression mapping, enabling reproducible, quantitative analysis of neural transcriptomes. His work has been instrumental in linking channelopathies to neurodevelopmental disorders, offering a template for studying brain-wide gene expression dynamics. With an impact that extends to systems neuroscience and drug target discovery, Carson’s digital atlas remains a vital tool for researchers exploring the molecular basis of brain function and disease.
Research Focus
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Top Papers
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