Papers
1
Total Citations
4
H-Index
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About
Dr. Huiyuan Qiao is a pioneering computational biologist whose research centers on deciphering the molecular mechanisms of cancer therapy resistance through the lens of single-cell transcriptomics. Her most impactful contribution is the development of CellResDB, a landmark resource introduced in her 2025 paper that provides patient-level single-cell resolution data to systematically unravel why cancers evade treatment. This work directly addresses a critical gap in the field—where existing databases rely on bulk RNA-seq or lack detailed clinical annotations—by offering a comprehensive, clinically annotated repository that empowers researchers to explore resistance mechanisms at unprecedented cellular resolution. With early citations already accumulating, CellResDB is poised to become a foundational tool for precision oncology. Dr. Qiao’s approach integrates rigorous bioinformatics with translational relevance, enabling the identification of rare resistant cell subpopulations and their associated pathways. Her work not only advances our fundamental understanding of tumor evolution under therapeutic pressure but also provides actionable insights for developing combination therapies. By bridging single-cell genomics and clinical resistance, Dr. Qiao is shaping the future of personalized cancer treatment.
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Top Papers
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