Hiroyuki Yanai
Papers
2
Total Citations
15
H-Index
2
About
Hiroyuki Yanai is a urological pathologist whose research focuses on improving diagnostic accuracy in prostate cancer, particularly through second-opinion pathology reviews. His major contributions center on the critical issue of Gleason grade group (GGG) discordance between needle-core biopsy and radical prostatectomy specimens. In his most-cited work (2020, 13 citations), Yanai demonstrated that even when biopsy specimens are reviewed by expert pathologists, a significant risk of pathological upgrading remains after surgery—highlighting the limitations of current biopsy-based risk stratification. His subsequent study (2021, 2 citations) directly showed that implementing a formal second-opinion pathology review significantly improves diagnostic concordance between biopsy and surgical specimens, reducing the rate of Gleason score misclassification. This work has practical implications for treatment decision-making, as accurate grading is essential for determining whether patients are candidates for active surveillance versus definitive therapy. Yanai’s research underscores the value of expert pathology review in prostate cancer management and provides evidence-based guidance for optimizing diagnostic workflows. His findings are particularly relevant for urologists, pathologists, and researchers working to reduce over- and under-treatment in prostate cancer.
Research Focus
Key Achievements
Top Papers
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- 2