Helga Gressmann
Papers
1
Total Citations
35
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1
About
Helga Gressmann is a toxicologist whose research focuses on the mutagenicity and chemical characterization of cigarette smoke, with particular emphasis on the health impacts of mainstream smoke and its gas/vapour phase. Her most cited work, "Mutagenicity of native cigarette mainstream smoke and its gas/vapour phase by use of different tester strains and cigarettes in a modified Ames assay" (2008, 35 citations), represents a significant contribution to environmental toxicology. In this study, Gressmann developed and applied a modified Ames assay to systematically compare the mutagenic potential of whole cigarette smoke versus its gas/vapour phase across multiple tester strains and cigarette types. Her findings helped clarify the relative contributions of particulate and gaseous components to smoke's genotoxicity, providing critical insights for regulatory toxicology and tobacco harm reduction. This work has been instrumental in shaping methodologies for assessing complex aerosol mixtures and has informed debates on product risk characterization. Gressmann's research continues to influence the field of inhalation toxicology, particularly in understanding how different smoke fractions contribute to DNA damage and carcinogenic risk.
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