Graeme C. McAlister
Papers
1
Total Citations
48
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1
About
Graeme C. McAlister is a leading figure in the development of cutting-edge proteomics technologies, with a primary focus on advancing mass spectrometry workflows for high-throughput, large-scale biological discovery. His most notable contribution is the creation of the AutoMP3 platform, an automated, 16-plex plasma proteomics system that integrates real-time search and ion mobility mass spectrometry. This groundbreaking work, detailed in his highly cited 2021 paper (48 citations), overcomes critical bottlenecks in sample preparation and instrument time, enabling the profiling of hundreds to thousands of samples with unprecedented speed and reproducibility. By applying this technology to comparative studies of naked mole-rats and mice, McAlister has opened new avenues for exploring aging and resilience at the proteome level. His innovations are instrumental in making deep, multiplexed proteomic analysis accessible for large-scale clinical and biological studies, cementing his reputation as a key architect of next-generation, automated proteomics platforms that are transforming the field.
Research Focus
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