Giuditta Mannelli

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About

Dr. Giuditta Mannelli is a leading figure in head and neck surgical oncology, with a primary focus on the evolving management of HPV-related oropharyngeal squamous cell carcinoma (OPSCC). Her research centers on the critical intersection of oncological efficacy and quality of life, particularly through the investigation of de-escalation strategies that minimize treatment morbidity. Her most cited work, "Role of TORS as De-Escalation Strategy in HPV-Related Oropharyngeal Cancer, What We Need to Know" (2024), has already garnered 14 citations, establishing her as a key voice in this rapidly advancing field. In this paper, Dr. Mannelli systematically examines how Transoral Robotic Surgery (TORS) can serve as a precise, less morbid alternative to traditional chemoradiation for select patients, offering a roadmap for clinicians navigating this paradigm shift. Her contributions are helping to redefine standards of care, ensuring that patients with favorable prognoses can achieve excellent oncological outcomes without enduring the long-term toxicities of aggressive therapy. Dr. Mannelli’s work is essential reading for surgeons and oncologists seeking to personalize treatment and improve survivorship in head and neck cancer.