G. Nozari
Papers
1
Total Citations
53
H-Index
1
About
Dr. G. Nozari is a geneticist whose research centers on high-throughput mutation detection and the molecular genetics of DNA repair disorders, with a particular focus on the ATM gene. Their most impactful contribution is the development and application of DOVAM-S (Detection Of Virtually All Mutations—SSCP), a comprehensive scanning method that overcame the formidable challenge of analyzing the massive ATM gene, which spans 66 exons and lacks mutational hotspots. By successfully scanning the entire coding region of ATM, Dr. Nozari’s 2003 study (53 citations) provided a critical tool for distinguishing pathogenic mutations from benign polymorphisms, significantly advancing the diagnosis of ataxia-telangiectasia and related cancer predisposition syndromes. This work has been foundational for subsequent genetic screening efforts, enabling more accurate identification of ATM variants in both research and clinical settings. Dr. Nozari’s methodological innovation has left a lasting impact on the field of human genetics, facilitating the study of large, complex genes and improving our understanding of DNA damage response pathways.
Research Focus
Key Achievements
Top Papers
- 1Comprehensive scanning of theATM gene with DOVAM-S53 citations · 2003