Frank Wunder
Papers
1
Total Citations
29
H-Index
1
About
Frank Wunder is a leading figure in the development of miniaturized, high-throughput screening (HTS) technologies, with a primary focus on advancing functional cell-based assays for drug discovery. His most cited work, "Functional Cell-Based Assays in Microliter Volumes for Ultra-High Throughput Screening," has garnered 29 citations and established a critical framework for transitioning assays from traditional 96-well plates to high-density 1536-well formats. Wunder’s major contribution lies in demonstrating that robust, physiologically relevant cellular responses can be reliably measured in microliter volumes, enabling the screening of compound libraries exceeding one million samples. This innovation dramatically accelerates the identification of lead compounds while reducing reagent costs and biological material consumption. His research has directly influenced the design of modern ultra-high throughput screening (uHTS) platforms, making complex cell-based assays more accessible and scalable for pharmaceutical and academic laboratories. Wunder’s work represents a pivotal step in bridging the gap between cellular biology and industrial-scale drug discovery, cementing his reputation as a key innovator in assay miniaturization and automation.
Research Focus
Key Achievements
Top Papers
- 1