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Francine Chassoux is a leading figure in epilepsy surgery, whose work has fundamentally shaped the practice of stereo-electroencephalography (SEEG). Her research focuses on the precise localization of epileptogenic zones, particularly in complex cases such as focal cortical dysplasia and temporal lobe epilepsy. Chassoux’s major contributions include refining SEEG methodology to improve surgical outcomes, notably through her seminal 2020 paper "A Practical Approach to Stereo EEG," which has garnered 17 citations and serves as a critical guide for clinicians. She has also pioneered the integration of advanced neuroimaging with electrophysiological data, enhancing the accuracy of seizure-onset zone identification. With over 100 publications, her work has been cited extensively, reflecting its profound impact on both clinical practice and neurosurgical research. Chassoux’s achievements include leading international collaborations and training a generation of epileptologists, solidifying her legacy as a transformative force in the field.