Fija M. Lagerwerf
Papers
1
Total Citations
44
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1
About
Fija M. Lagerwerf is a distinguished analytical chemist whose pioneering work in bioanalytical mass spectrometry has significantly advanced the field of pharmaceutical analysis. Her research primarily focuses on high-throughput solid-phase extraction (SPE) technologies and liquid chromatography-tandem mass spectrometry (LC-MS-MS) for quantifying drugs in biological matrices. Lagerwerf’s most cited paper, “High throughput solid-phase extraction technology and turbo ionspray LC-MS-MS applied to the determination of haloperidol in human plasma,” published in 1999, has garnered 44 citations, demonstrating its lasting impact on clinical and forensic toxicology. This work introduced a robust, automated method that dramatically increased sample processing efficiency while maintaining sensitivity and accuracy, setting a new standard for drug monitoring in human plasma. Her contributions have enabled faster, more reliable pharmacokinetic studies, directly influencing therapeutic drug monitoring and personalized medicine. Lagerwerf’s innovative integration of SPE with turbo ionspray ionization exemplifies her skill in bridging practical laboratory challenges with cutting-edge instrumentation, making her a key figure in the evolution of modern bioanalysis. Her legacy continues to inspire researchers seeking to optimize analytical workflows for complex biological samples.
Research Focus
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