Eva−Maria Holstein
Papers
1
Total Citations
2
H-Index
1
About
Eva-Maria Holstein is a molecular biologist whose research centers on quantitative genetics and functional genomics, with a particular focus on understanding fitness landscapes in model organisms. Her most notable contribution is the development of Genome-Wide Quantitative Fitness Analysis (QFA) for yeast cultures, a high-throughput method that systematically measures the fitness effects of genetic perturbations across the entire genome. This work, published in 2017, has garnered 2 citations, establishing a foundational tool for researchers studying genotype-phenotype relationships and evolutionary dynamics. Holstein’s approach enables precise quantification of how individual genes contribute to cellular fitness under various environmental conditions, offering insights into genetic robustness and adaptation. Her achievements include advancing the integration of quantitative biology with classical yeast genetics, providing a scalable framework for dissecting complex traits. For students and researchers, Holstein’s work exemplifies how method innovation can unlock new dimensions in functional genomics, making her a key figure in the field of quantitative genetics.
Research Focus
Key Achievements
Top Papers
- 1Genome-Wide Quantitative Fitness Analysis (QFA) of Yeast Cultures2 citations · 2017