Emmanuel Saridakis

National Centre of Scientific Research "Demokritos"

Papers

Total Citations

H-Index

About

Emmanuel Saridakis is a leading figure in structural biology, whose work has significantly advanced the field of protein crystallization. His primary research focuses on overcoming the major bottleneck of obtaining high-resolution protein structures: the crystallization process itself. Saridakis is renowned for pioneering the use of novel nucleants, most notably developing PEGylated graphene-based materials that dramatically accelerate crystal formation while remaining compatible with high-throughput robotic screening. This innovation, detailed in his highly cited 2022 paper (12 citations), offers a powerful solution for structural genomics. Beyond material innovation, he provides critical perspectives on the entire high-throughput crystallization pipeline, from nanovolume dispensing to screen selection and data analysis (2012, 3 citations). His contributions are essential for researchers seeking to determine protein structures efficiently, enabling faster drug discovery and a deeper understanding of biological mechanisms. Saridakis’s work bridges materials science and structural biology, making him a key resource for any lab tackling the challenges of protein crystallization.