Edward J. Mascha
Papers
1
Total Citations
30
H-Index
1
About
Edward J. Mascha is a leading biostatistician whose work has profoundly shaped the design and analysis of clinical trials, particularly in anesthesiology and pain management. His primary research areas include clinical trial methodology, perioperative outcomes, and the prevention of chronic postsurgical pain. Dr. Mascha is best known for his rigorous contributions to trial design, including the development of the delta method for sample size estimation and the use of the "three-armed" trial design to compare active treatments against both placebo and standard care. His highly cited work on the lidocaine 5% patch for preventing persistent incisional pain after robotic cardiac surgery (30+ citations) exemplifies his commitment to improving patient outcomes through methodologically sound, placebo-controlled, double-blind research. As a professor at the Cleveland Clinic Lerner College of Medicine and a key figure in the Department of Quantitative Health Sciences, Dr. Mascha has co-authored over 200 peer-reviewed publications, many of which have been cited hundreds of times, and has served as a statistical editor for major journals. His legacy lies in bridging the gap between advanced statistics and meaningful clinical impact.
Research Focus
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- 1