Douglas T. Gjerde

About

Douglas T. Gjerde is a leading innovator in bioanalytical chemistry, with a focus on advancing mass spectrometry and glycoproteomics. His work centers on developing novel materials and microcolumn technologies for the rapid, high-affinity capture and release of biomolecules. A key contribution is the creation of immobilized PNGase F microcolumns for ultra-fast N-glycan release from glycoproteins, a technique that streamlines glycoprotein analysis and has garnered 47 citations. Gjerde also pioneered material-enhanced laser desorption/ionization (MELDI) using derivatized poly(glycidyl methacrylate/divinylbenzene) supports for ultra-fast mass fingerprinting of peptides and proteins from complex samples like serum and cell lysates. This material-based approach, cited 31 times, enables high-throughput screening for diagnostic markers via MALDI-TOF MS. His work bridges material science and proteomics, offering practical tools for biomarker discovery and disease diagnostics. Gjerde’s contributions have significantly impacted the efficiency and sensitivity of protein and glycan analysis, making him a notable figure in the field of analytical biochemistry.

Research Focus

Key Achievements

Top Papers

1. 1
   Rapid N -glycan release from glycoproteins using immobilized PNGase F microcolumns

   47 citations · 2016
2. 2
   Ultra‐fast mass fingerprinting by high‐affinity capture of peptides and proteins on derivatized poly(glycidyl methacrylate/divinylbenzene) for the analysis of serum and cell lysates

   31 citations · 2006

Key Collaborators

Contact & Links