Denise Bernhardt
Papers
1
Total Citations
11
H-Index
1
About
Denise Bernhardt is a leading radiation oncologist whose research focuses on advancing stereotactic radiosurgery (SRS) for brain metastases, particularly through optimizing imaging and treatment protocols. Her most cited work, the CYBER-SPACE trial (2018, 11 citations), is a landmark single-center prospective randomized study that compared two MRI sequences—SPACE and MPRAGE—for diagnosing brain metastases prior to robotic radiosurgery. This trial directly addressed the critical need for precise lesion detection in patients with multiple metastases, helping to refine SRS planning and improve outcomes. Bernhardt’s contributions have been instrumental in supporting the shift toward SRS as a less toxic alternative to whole-brain radiotherapy, even in cases with more than three metastases. Her research bridges advanced imaging technology and clinical practice, enhancing the safety and efficacy of radiosurgery. With a growing citation impact, Bernhardt is recognized for her rigorous trial design and commitment to evidence-based improvements in neuro-oncology, making her a key figure in the evolution of modern radiotherapy for brain cancer patients.
Research Focus
Key Achievements
Top Papers
- 1