David W. Thomas
Papers
2
Total Citations
259
H-Index
2
About
David W. Thomas is a leading researcher in antimicrobial resistance and glycobiology, whose work focuses on harnessing natural polymers to combat drug-resistant infections. His major contributions center on the discovery and characterization of OligoG, a low-molecular-weight alginate oligosaccharide derived from seaweed, which disrupts biofilms and potentiates the activity of conventional antibiotics. His highly cited 2012 paper (170 citations) demonstrates how OligoG overcomes drug resistance in bacteria, while his 2014 study (89 citations) extends this approach to fungal pathogens, including *Candida* and *Aspergillus* species. By showing that OligoG not only inhibits fungal growth but also enhances the efficacy of existing antifungals, Thomas has opened new avenues for treating stubborn, biofilm-associated infections. His work addresses a critical global health challenge—the rising prevalence of multidrug-resistant pathogens—with a novel, nature-inspired strategy. With over 250 combined citations for these two landmark studies alone, Thomas has established himself as a key figure in the development of anti-biofilm and antibiotic-potentiating therapies, offering promising solutions for both bacterial and fungal infections.
Research Focus
Key Achievements
Top Papers
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