David Joseph
Papers
1
Total Citations
8
H-Index
1
About
David Joseph is a pioneering urologic surgeon and researcher whose work centers on neurogenic bladder, spina bifida, and innovative reconstructive surgical techniques. His most impactful contribution is the development and clinical testing of the Tengion Autologous Neo-Bladder Augment™ (NBA), a groundbreaking tissue-engineered approach for augmentation cystoplasty in patients with neurogenic bladder secondary to spina bifida. This Phase 2 study, with 8 citations, represents a paradigm shift from traditional bowel-based bladder augmentation toward regenerative medicine solutions. Joseph’s research addresses the complex challenge of rectovesical fistula following radical prostatectomy, demonstrating his expertise in managing severe urologic complications. His work bridges the gap between pediatric urology and adult reconstructive surgery, offering new hope to patients with congenital and acquired bladder dysfunction. By pioneering tissue-engineered bladder augmentation, Joseph has opened doors to reducing the morbidity associated with traditional enterocystoplasty, including metabolic disturbances and malignancy risk. His contributions continue to influence the field of regenerative urology, inspiring further investigation into autologous tissue engineering for genitourinary reconstruction.
Research Focus
Key Achievements
Top Papers
- 1