Dari Shalon
Papers
2
Total Citations
11,202
H-Index
2
About
Dari Shalon is a pioneering molecular biologist whose groundbreaking work in the mid-1990s fundamentally transformed how scientists study gene expression. Best known as a key architect of cDNA microarray technology, Shalon helped revolutionize genomics by enabling researchers to monitor thousands of genes simultaneously rather than one at a time — a paradigm shift that accelerated discovery across biology and medicine. Her landmark 1995 paper, "Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray," introduced a high-speed robotic printing system for depositing cDNAs onto glass slides, creating dense, miniaturized arrays capable of measuring gene activity with remarkable precision. This work has accumulated an extraordinary 9,594 citations, cementing its status as one of the most influential publications in genomics history. Building on this foundation, her 1996 follow-up demonstrated the technology's scalability to human genomes, successfully profiling over 1,000 human genes using a sensitive two-color hybridization approach — garnering an additional 1,608 citations. Shalon's contributions laid essential groundwork for the modern era of functional genomics, influencing fields ranging from cancer biology to drug discovery, and inspiring a generation of researchers to think about gene regulation at a systems-wide level.
Research Focus
Key Achievements
Top Papers
- 1Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray9,594 citations · 1995
- 2Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.1,608 citations · 1996