Daniela G. Seidler
Papers
1
Total Citations
12
H-Index
1
About
Daniela G. Seidler is a leading researcher in glycobiology, with a primary focus on the structural analysis of glycosaminoglycans (GAGs)—specifically chondroitin sulfate (CS) and dermatan sulfate (DS). Her work centers on elucidating the complex sulfation patterns of these carbohydrate chains, which are critical for understanding their roles in brain development and disease. A major contribution is her development of advanced mass spectrometry (MS) methodologies, including chip-nanoelectrospray multistage MS²-MS⁴ combined with high-resolution MS, to identify and characterize rare, highly sulfated motifs. In her highly cited 2013 study, she applied this technique to discover an unusually sulfated tetrasaccharide motif in mouse brain, revealing a novel structural complexity in neural GAGs. This work has been foundational for researchers studying how specific sulfation patterns influence cell signaling and neurobiology. With 12 citations on this key paper, her impact is evident in the field of analytical glycobiology, where her methods are now used to probe the functional significance of GAG modifications. Her achievements highlight her as a pioneer in pushing the boundaries of carbohydrate sequencing.
Research Focus
Key Achievements
Top Papers
- 1