D. Michael Ando
Papers
2
Total Citations
22
H-Index
2
About
D. Michael Ando is a neuroscientist and bioengineer whose work sits at the intersection of high-throughput imaging and neurodegenerative disease research. His primary contributions center on developing automated, quantitative methods to study how misfolded proteins drive neuronal death in conditions like ALS and Huntington’s disease. Ando pioneered a form of robotic microscopy that enables the longitudinal tracking of thousands of individual neurons over time, a breakthrough that allows researchers to observe the real-time effects of toxic proteins and potential therapeutic interventions at single-cell resolution. His most cited paper (2013, 12 citations) introduced this automated imaging and analysis platform for neurons expressing polyglutamine-expanded proteins, while his subsequent work (2016, 10 citations) extended the approach to model survival dynamics in ALS, using a three-groups statistical framework to interpret high-throughput screening data. Though his citation counts are modest, Ando’s methodological innovations have laid critical groundwork for large-scale, unbiased drug discovery in neurodegeneration. His work exemplifies how engineering and biology can converge to create powerful new tools for understanding—and ultimately treating—devastating neurological disorders.
Research Focus
Key Achievements
Top Papers
- 1
- 2A Three-Groups Model for High-Throughput Survival Screens10 citations · 2016