Crina Tiron
Papers
1
Total Citations
25
H-Index
1
About
Dr. Crina Tiron is a cancer biologist whose research focuses on the cellular and molecular mechanisms driving drug resistance and tumor progression. Her key contributions lie in understanding how the tumor microenvironment influences epithelial plasticity, a process that allows cancer cells to switch between states and evade therapy. In her highly cited 2018 work (25 citations), Dr. Tiron provided compelling evidence that specific microenvironments can impose non-sporadic, or widespread, expression of the AXL and cKIT receptors, linking this to drug resistance. This finding challenges the prevailing model of rare, stochastic resistance and highlights the microenvironment's active role in shaping tumor behavior. Her work has significant implications for developing more effective, combination therapies that target both cancer cells and their supportive niche. Dr. Tiron’s research is foundational for students and researchers interested in the dynamic interplay between cancer cells and their surroundings, and her insights into epithelial plasticity are paving the way for novel strategies to overcome therapeutic failure.
Research Focus
Key Achievements
Top Papers
- 1