Christopher McFaul
Papers
1
Total Citations
114
H-Index
1
About
Dr. Christopher McFaul is a leading researcher in the genetics of pancreatic disease, with a particular focus on cystic fibrosis (CF) and its connection to idiopathic chronic pancreatitis (ICP). His seminal 2005 study, cited over 114 times, fundamentally advanced our understanding of how CFTR gene mutations contribute to pancreatitis. In this landmark work, Dr. McFaul demonstrated that individuals carrying a single CF-causing mutation—who are not diagnosed with cystic fibrosis—face a significantly increased risk of developing idiopathic chronic pancreatitis. He further clarified that the risk is highest in those with a CF-causing mutation combined with a second pathogenic CFTR allele, a finding that reshaped clinical screening and genetic counseling for pancreatitis patients. This contribution bridged a critical gap between classic CF and isolated pancreatic disease, highlighting the spectrum of CFTR-related disorders. Dr. McFaul’s research continues to inform how clinicians assess genetic risk in unexplained pancreatitis, making his work essential reading for gastroenterologists and geneticists alike.
Research Focus
Key Achievements
Top Papers
- 1Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers114 citations · 2005