Christopher Benevides
Papers
1
Total Citations
43
H-Index
1
About
Christopher Benevides is a pioneering figure in high-throughput bioanalysis, whose work has fundamentally advanced the efficiency of liquid chromatography/tandem mass spectrometry (LC/MS/MS) in pharmaceutical research. His key contributions center on the development and validation of 384-well format solid phase extraction (SPE), a technique that dramatically accelerates sample preparation for clinical and preclinical studies. In his landmark 2000 paper, which has garnered 43 citations, Benevides demonstrated the practical application of this method by successfully extracting the 5-HT agonist sumatriptan from human plasma, effectively creating a "clinical trial on a plate." This innovation enabled researchers to process hundreds of samples simultaneously, reducing time and solvent use while maintaining analytical precision. His work has been instrumental in bridging the gap between high-throughput screening and rigorous bioanalytical validation, making him a respected authority in the field. Benevides’ achievements continue to influence modern drug development, where rapid, reliable bioanalysis is critical for moving candidates from bench to bedside.
Research Focus
Key Achievements
Top Papers
- 1