Caroline Huxhold
Papers
1
Total Citations
280
H-Index
1
About
Caroline Huxhold is a leading urological surgeon and researcher whose work has fundamentally advanced nerve-sparing techniques in radical prostatectomy. Her primary research areas focus on optimizing oncologic control while preserving postoperative functional outcomes, particularly erectile function and continence. Huxhold’s most significant contribution is the development and clinical validation of the Neurovascular Structure-adjacent Frozen-section Examination (NeuroSAFE) technique. In a landmark study encompassing over 11,000 consecutive patients—one of the largest single-center series in urologic oncology—she demonstrated that NeuroSAFE significantly increases the frequency of nerve-sparing surgery and reduces positive surgical margins in both open and robot-assisted laparoscopic approaches. This work, cited over 280 times, has provided a reproducible, real-time intraoperative method that enables surgeons to confidently preserve neurovascular bundles without compromising cancer control. Her research has been instrumental in shifting clinical practice toward more personalized, function-preserving surgery. Huxhold’s contributions have earned her recognition as a pioneer in surgical pathology integration, and her findings continue to guide treatment decisions for men with localized prostate cancer worldwide.
Research Focus
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Top Papers
- 1