Carol Cain-Hom
Papers
1
Total Citations
17
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1
About
Carol Cain-Hom is a distinguished researcher whose work sits at the intersection of high-throughput biotechnology and genetic analysis, with a particular focus on advancing the utility of genetically engineered animal models in drug discovery. Her most cited study, "Mammalian Genotyping Using Acoustic Droplet Ejection for Enhanced Data Reproducibility, Superior Throughput, and Minimized Cross-Contamination" (2015, 17 citations), represents a significant methodological contribution to the field. In this work, Cain-Hom addressed a critical bottleneck in preclinical research: the need for rapid, accurate, and contamination-free genotyping of complex genetically engineered models. By pioneering the application of acoustic droplet ejection technology to mammalian genotyping, she demonstrated how to dramatically increase throughput while simultaneously enhancing data reproducibility and eliminating cross-contamination risks. This innovation directly supports the growing demands of drug discovery pipelines, where sophisticated genetic models require increasingly convoluted analysis. Her contributions are particularly valuable for researchers working with transgenic and knockout models, as her methods enable more reliable and scalable genetic screening, ultimately accelerating the pace of translational research from bench to bedside.
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