Carlos L. Arteaga

Vanderbilt University, Breast Cancer Research Foundation

Papers

Total Citations

228

H-Index

About

Carlos L. Arteaga is a pioneering figure in cancer biology, with a career defined by transformative contributions to the understanding of breast cancer and growth factor signaling. His research centers on the molecular mechanisms driving tumor progression, particularly the roles of transforming growth factor-beta (TGF-β) and the HER2/Neu (ErbB2) oncogene in mammary epithelial cells. A standout achievement is his development of a novel histology-directed strategy for MALDI-MS tissue profiling, which dramatically improves throughput and cellular specificity in human breast cancer analysis—a method that has garnered 187 citations for its impact on precision oncology. Arteaga also advanced proteomics through multivariable difference gel electrophoresis and mass spectrometry (DIGE/MS), revealing how TGF-β receptor activation alters protein expression and post-translational modifications in HER2-overexpressing cells (41 citations). His work bridges cutting-edge technology and clinical relevance, offering insights into therapeutic resistance and tumor heterogeneity. As a leader in translational research, Arteaga’s innovations continue to shape how scientists profile tumors and target signaling pathways, making him an influential voice in the fight against cancer.