Britta Kleine
Papers
1
Total Citations
138
H-Index
1
About
Britta Kleine is a leading figure in bioprocess engineering, whose work centers on the development of high-throughput, automated platforms for microbial cultivation and optimization. Her major contribution lies in bridging the gap between rapid strain screening and quantitative, scalable bioprocess development. Her most cited work, "An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform" (2012, 138 citations), introduced a transformative approach that moves beyond simple binary "high/low productivity" readouts. By integrating a novel microbioreactor with automated liquid handling, she enabled the acquisition of key kinetic and physiological parameters—such as growth rates and product yields—directly from microscale cultures. This innovation has proven critical for accelerating the development of heterologous protein production processes, allowing researchers to generate industrially relevant data earlier in the pipeline. Kleine’s work has had a profound impact on the field, providing a practical, scalable solution that reduces the time and cost of bioprocess optimization. Her achievements have established a new standard for high-throughput experimentation, making her a pivotal contributor to the advancement of modern biomanufacturing.
Research Focus
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Top Papers
- 1