Brett Larsen
Papers
1
Total Citations
35
H-Index
1
About
Brett Larsen is a distinguished researcher in the field of proteomics, with a primary focus on advancing mass spectrometry-based methods for protein identification and characterization. His most-cited work, "Peptide End Sequencing by Orthogonal MALDI Tandem Mass Spectrometry" (2002, 35 citations), introduced a highly sensitive approach to peptide fragmentation that enabled more reliable identification of proteins from sequence databases. This work addressed a critical bottleneck in proteomics by improving the accuracy of peptide sequencing directly from MALDI-generated ions, complementing the then-standard two-layered strategy of MALDI peptide mass fingerprinting followed by electrospray tandem mass spectrometry. Larsen’s contributions have helped shape modern proteomic workflows, particularly in the analysis of complex biological samples where sensitivity and precision are paramount. His research continues to influence the development of robust analytical pipelines for protein discovery, making him a respected figure in the mass spectrometry community.
Research Focus
Key Achievements
Top Papers
- 1Peptide End Sequencing by Orthogonal MALDI Tandem Mass Spectrometry35 citations · 2002