Brett A. Stillman

Papers

Total Citations

135

H-Index

About

Brett A. Stillman is a leading figure in the development of microarray technology, with his most influential work centering on the creation of novel substrates for high-throughput biological analysis. His primary research area involves the engineering of advanced surfaces for the immobilization of biomolecules, a critical component in the evolution of genomics and proteomics. Stillman’s major contribution is the invention and characterization of FAST™ Slides, a groundbreaking microporous polymeric surface that revolutionized microarray applications. This nitrocellulose-based polymer, detailed in his seminal 2000 paper (cited over 135 times), binds DNA and proteins in a noncovalent yet irreversible manner, offering superior sensitivity and compatibility with robotic systems. By providing a robust, user-friendly platform, Stillman’s work enabled more reliable and scalable assays, accelerating research in gene expression profiling and protein interaction studies. His innovation remains a foundational tool in the field, demonstrating how material science can directly enhance the capabilities of molecular biology. For students and researchers, Stillman’s contributions exemplify the power of interdisciplinary engineering in driving biotechnological breakthroughs.