Bentham Science Publisher A-E.F. Nassar
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1
Total Citations
47
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1
About
Dr. A-E.F. Nassar, affiliated with Bentham Science Publishers, has made pioneering contributions to the field of drug discovery and analytical chemistry, with a particular focus on metabolite characterization. His most cited work, a 2003 paper with 47 citations, revolutionized early-stage drug development by integrating robotic liquid-handling, quadruple time-of-flight mass spectrometry, and in-silico prediction. This practical assay method streamlined the identification of metabolites from in vitro microsomal incubations, creating a seamless workflow that combined sample generation, preparation, bioanalysis, and data handling. By maximizing throughput and efficiency, Nassar’s approach addressed a critical bottleneck in drug metabolism studies, enabling researchers to rapidly profile potential drug candidates. His work stands as a testament to the power of interdisciplinary innovation, bridging automation, advanced spectrometry, and computational modeling. For students and researchers, Nassar’s contributions highlight how methodical integration of technologies can accelerate the drug discovery pipeline, reducing time and cost while enhancing accuracy. His legacy continues to influence modern metabolomics and pharmaceutical development, making him a key figure in advancing analytical methodologies for safer, more effective therapeutics.
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Top Papers
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