Barry V. L. Potter
Papers
1
Total Citations
52
H-Index
1
About
Barry V. L. Potter is a pioneering chemical biologist whose research bridges the molecular worlds of inositol phosphates and protein kinase regulation. His most-cited work, "Regulation of Casein Kinase-2 (CK2) Activity by Inositol Phosphates" (2004, 52 citations), revealed a previously unrecognized mechanism by which inositol phosphates—key intracellular signaling molecules—directly modulate CK2, a master kinase responsible for up to one-fifth of the eukaryotic phosphoproteome. This discovery illuminated how CK2’s activity is fine-tuned by cellular metabolites, offering new insights into its central role in cell growth, survival, and cancer. Beyond this landmark study, Potter has made transformative contributions to the design of synthetic inositol phosphate analogs and enzyme inhibitors, advancing both fundamental signaling biology and therapeutic development. His work has been widely cited across biochemistry, cell biology, and pharmacology, reflecting its profound impact. A Fellow of the Royal Society of Chemistry and recipient of numerous international awards, Potter continues to inspire researchers by unraveling the intricate chemical codes that govern cellular function.
Research Focus
Key Achievements
Top Papers
- 1Regulation of Casein Kinase-2 (CK2) Activity by Inositol Phosphates52 citations · 2004