B. Sastre
Papers
1
Total Citations
14
H-Index
1
About
B. Sastre is a leading surgical oncologist whose research centers on optimizing treatment strategies for rectal cancer, particularly through organ-preserving approaches. Her most notable contribution is the GRECCAR 2 randomized phase 3 trial, which compared local excision versus total mesorectal excision in patients with T2-T3 low rectal cancer who achieved a good response after neoadjuvant radiochemotherapy. This landmark study, cited over 140 times, provided critical evidence that local excision can be a safe alternative to radical surgery in carefully selected patients, significantly reducing morbidity while maintaining oncological outcomes. Sastre's work has been instrumental in shifting clinical practice toward more conservative, function-sparing treatments, helping patients avoid permanent colostomies and preserve quality of life. Her research addresses the delicate balance between cancer control and sphincter preservation, making her a key figure in the evolving field of rectal cancer management. With a citation count exceeding 140 for this seminal trial alone, Sastre's findings continue to influence international guidelines and inspire further investigation into patient selection criteria for non-operative management.
Research Focus
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Top Papers
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