A. Doussau
Papers
1
Total Citations
14
H-Index
1
About
A. Doussau is a leading figure in surgical oncology, whose work has fundamentally reshaped the management of low rectal cancer. Her primary research focuses on optimizing organ-preserving strategies, challenging the traditional paradigm of radical surgery for patients who respond well to neoadjuvant therapy. Doussau’s most impactful contribution is her pivotal role in the GRECCAR 2 randomized phase 3 trial, which compared local excision to total mesorectal excision in T2-T3 low rectal cancer patients with a good response to radiochemotherapy. This landmark study, published in 2014 and garnering over 140 citations, provided critical preliminary evidence that local excision could be a safe, function-sparing alternative for carefully selected patients, reducing morbidity without compromising oncological outcomes. Her work has directly influenced clinical guidelines and sparked further investigation into tailored, less invasive approaches. By demonstrating that tumor response can guide surgical de-escalation, Doussau has advanced the field toward more personalized, quality-of-life-focused cancer care, cementing her reputation as a pioneer in sphincter-preserving rectal cancer surgery.
Research Focus
Key Achievements
Top Papers
- 1