B. Matthew Fagan

Papers

Total Citations

H-Index

About

B. Matthew Fagan is a biomedical researcher whose work focuses on the intersection of cancer biology and immunology, particularly the role of neutrophil extracellular traps (NETs) in tumor progression. His most notable contribution is the 2024 study "Pancreatectomy Induces Cancer-Promoting Neutrophil Extracellular Traps," which has already garnered 5 citations, signaling its emerging impact. This research demonstrates that the surgical stress of pancreatectomy can trigger the formation of NETs—web-like structures released by neutrophils—that paradoxically create a pro-tumorigenic microenvironment, potentially accelerating cancer recurrence. By linking surgical intervention to immune-mediated cancer promotion, Fagan’s work challenges conventional assumptions about postoperative recovery and opens new avenues for therapeutic intervention, such as targeting NET formation to improve patient outcomes. His findings are particularly relevant for pancreatic cancer, one of the most aggressive malignancies, where surgical resection remains a primary treatment. Fagan’s research bridges basic immunology and clinical oncology, offering insights that could reshape perioperative care. With this foundational study, he is establishing himself as a rising voice in cancer immunology, poised to influence both laboratory investigation and translational medicine.