Amanda Puleo

Papers

Total Citations

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About

Amanda Puleo is a rising researcher in cancer biology and immunology, with a focused interest in the tumor microenvironment and the role of innate immune responses in cancer progression. Her most notable work, "Pancreatectomy Induces Cancer-Promoting Neutrophil Extracellular Traps" (2024), has already garnered 5 citations, signaling its early impact in the field. In this study, Puleo and her team demonstrated that the surgical stress of pancreatectomy triggers the formation of neutrophil extracellular traps (NETs), which in turn promote a pro-tumorigenic environment. This finding challenges conventional assumptions about postoperative recovery and opens new avenues for therapeutic intervention to prevent cancer recurrence. By linking surgical trauma directly to immune-mediated cancer promotion, Puleo’s work bridges oncology and immunology, offering potential strategies to mitigate metastasis risk after pancreatic surgery. Her research is particularly significant given the aggressive nature of pancreatic cancer and the urgent need for improved prognostic and therapeutic approaches. As an early-career scientist, Puleo’s contributions highlight her ability to identify clinically relevant mechanisms, positioning her as a promising voice in cancer immunology and surgical oncology.