April Toledo Vo
Papers
8
Total Citations
110
H-Index
3
About
April Toledo Vo is a pioneering researcher in the field of oral biotherapeutic delivery, whose work is transforming how patients receive treatments for chronic conditions. Her primary research focuses on developing an orally ingestible robotic pill that can safely and effectively deliver large-molecule drugs—such as antibodies, peptides, and hormones—which have traditionally required painful injections. Vo’s major contributions include demonstrating that this robotic pill achieves high bioavailability comparable to parenteral administration in both preclinical and clinical settings. Her landmark 2021 study on the pill’s safety and tolerability in healthy subjects has garnered 94 citations, underscoring its significance. She has also led phase 1 trials showing reliable delivery of teriparatide for osteoporosis and a biosimilar of ustekinumab, with bioavailability rivaling subcutaneous injections. Notably, her work extends to delivering GLP-1 agonists and follicle-stimulating hormone, offering hope for needle-free management of diabetes, obesity, and fertility disorders. By addressing poor patient compliance due to injection pain, Vo’s innovations promise to revolutionize chronic disease care, making her a leading figure in drug delivery science.
Research Focus
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