Apolline Monfilliette-Djelad

Université de Lille, Centre Hospitalier Universitaire de Lille

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About

Apolline Monfilliette-Djelad is a pioneering neurosurgeon whose work centers on advancing minimally invasive techniques for diagnosing and treating complex brainstem pathologies. Her primary research focus is the refinement of frameless robot-assisted stereotactic biopsies, a critical innovation for safely accessing the brainstem—a region traditionally considered high-risk for surgical intervention. Her landmark study, "Frameless robot-assisted stereotactic biopsies for lesions of the brainstem—a series of 103 consecutive biopsies" (2022), with 24 citations, represents one of the largest clinical series in this niche field. This work demonstrates the feasibility, accuracy, and safety of robotic guidance in obtaining tissue samples from deep-seated brainstem lesions, significantly reducing patient morbidity compared to older frame-based methods. By systematically analyzing outcomes across a substantial cohort, Monfilliette-Djelad has provided robust evidence that robotic assistance can achieve diagnostic yields comparable to conventional techniques while minimizing complications. Her contributions are reshaping neurosurgical standards for brainstem lesion management, offering new hope for patients with previously inoperable conditions. Her research continues to influence the integration of robotics into stereotactic neurosurgery, making her a key figure in the evolution of precision medicine for the central nervous system.