Anne Monette
Papers
1
Total Citations
187
H-Index
1
About
Dr. Anne Monette’s research lies at the intersection of extracellular matrix biology and vitamin K-dependent protein function, with a particular focus on the role of periostin in mesenchymal stromal cells. Her landmark 2008 study, cited 187 times, revealed that periostin is a member of a novel family of vitamin K-dependent proteins, demonstrating that this matricellular protein undergoes γ-carboxylation—a post-translational modification previously associated with only a handful of proteins. This work fundamentally expanded the known repertoire of Gla-containing proteins and opened new avenues for understanding how vitamin K influences stromal cell behavior and tissue remodeling. Beyond this discovery, Dr. Monette’s contributions have illuminated the broader significance of periostin in development and disease, particularly in fibrosis and cancer. Her findings have been instrumental in reshaping how researchers view the interplay between post-translational modifications and extracellular matrix signaling. With her work continuing to influence fields from regenerative medicine to oncology, Dr. Monette stands as a pivotal figure in unraveling the molecular complexity of vitamin K-dependent pathways in non-classical contexts.
Research Focus
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Top Papers
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