Andrew Bayley
Papers
4
Total Citations
505
H-Index
4
About
Andrew Bayley is a leading clinical researcher in head and neck oncology, whose work has fundamentally shaped the management of oropharyngeal squamous cell carcinoma (OPSCC). His primary research areas focus on treatment de-escalation and the comparative effectiveness of radiotherapy versus transoral robotic surgery (TORS). Bayley is best known as the principal investigator of the landmark ORATOR trial, a phase 2 randomized study that directly compared radiotherapy to TORS with neck dissection for OPSCC. The initial 2019 publication of this work has garnered over 458 citations, establishing it as a pivotal reference in the field. The final results, published in 2024, provide crucial long-term outcome data that continue to inform clinical decision-making. Beyond this, Bayley has made significant contributions to understanding lymphatic spread, notably through his research on contralateral nodal failure rates and the use of pre-operative SPECT-CT lymphatic mapping to guide unilateral neck management. His work has helped refine surgical approaches, reducing the need for bilateral neck treatment in carefully selected patients, thereby minimizing morbidity without compromising oncological safety.
Research Focus
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