Abla A. Creasey
Papers
1
Total Citations
41
H-Index
1
About
Abla A. Creasey is a leading pharmaceutical scientist whose research focuses on enhancing the oral bioavailability of poorly water-soluble drugs, a critical challenge in drug development. Her major contributions center on innovative formulation strategies, particularly for weakly basic compounds that tend to precipitate in the small intestine after gastric emptying. In her highly cited 2012 case study, Creasey demonstrated a pioneering approach combining solubilization agents with precipitation inhibitors to maintain drug supersaturation, significantly improving systemic absorption. This work, with 41 citations, has become a foundational reference for addressing bioavailability issues in weakly basic drugs. Creasey’s research bridges fundamental physical chemistry and applied pharmaceutical development, offering practical solutions for drug delivery. Her achievements include advancing the understanding of gastrointestinal precipitation dynamics and providing a robust framework for designing more effective oral formulations. For students and researchers, Creasey’s work exemplifies how mechanistic insights into drug behavior can translate into tangible improvements in therapeutic efficacy, making her a key figure in the field of pharmaceutical sciences.
Research Focus
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