Victoria Kearns

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About

Dr. Victoria Kearns is a leading figure in ocular biomechanics and retinal drug delivery, whose work is reshaping how novel gene and cell therapies reach the retina. Her primary research focuses on the mechanical optimization of subretinal injections—a technique critical for delivering therapeutics with precision to the subretinal space. In her landmark 2024 study, "Biomechanical considerations for optimising subretinal injections," which has already garnered 17 citations, Dr. Kearns systematically analyzed how injection parameters such as needle gauge, injection speed, and entry point influence retinal tissue stress and fluid distribution. This work provides a quantitative framework for clinicians to target specific retinal locations while minimizing iatrogenic damage, directly addressing a longstanding challenge in ocular gene therapy. Her contributions are particularly notable for bridging engineering principles with clinical practice, offering evidence-based guidelines that enhance the safety and efficacy of treatments for inherited retinal diseases. By defining the mechanical limits of retinal tissue during injection, Dr. Kearns has laid the groundwork for more predictable and reproducible therapeutic outcomes, making her a pivotal voice in the advancement of precision ophthalmology.