Shylaja Ramlal

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About

Shylaja Ramlal is a prominent researcher in the fields of molecular diagnostics and aptamer technology, with a particular focus on developing innovative tools for pathogen detection and protein targeting. Her most influential work, the 2015 paper "A combinatorial systematic evolution of ligands by exponential enrichment method for selection of aptamer against protein targets," has garnered 30 citations and stands as a cornerstone in the field of aptamer engineering. In this study, Ramlal introduced a refined SELEX methodology that dramatically improved the efficiency and specificity of aptamer selection against protein targets, addressing a critical bottleneck in the development of diagnostic and therapeutic agents. Her contributions have enabled the creation of high-affinity aptamers for a range of biomedically relevant proteins, with applications spanning biosensing, imaging, and targeted drug delivery. Beyond this seminal work, Ramlal has published extensively on the use of aptamers for detecting foodborne pathogens and toxins, earning recognition for bridging fundamental research with practical, real-world solutions. Her research has been cited over 200 times, reflecting its significant impact on the scientific community. Ramlal’s achievements include multiple patents and collaborations with industry partners, solidifying her reputation as a leader in the translation of aptamer-based technologies from bench to bedside.