Shibo Jiang
Papers
2
Total Citations
63
H-Index
2
About
Shibo Jiang is a prominent virologist and immunologist whose research has made significant contributions to the field of antiviral drug discovery, with a particular focus on HIV-1 entry and fusion inhibition. His work centers on developing innovative screening methodologies to identify therapeutic agents capable of blocking viral entry into host cells — a critical step in combating HIV/AIDS. Among his most notable contributions, Jiang pioneered high-throughput screening platforms for HIV-1 inhibitors, including a rapid fluorescence-linked immunosorbent assay targeting the gp41 fusion protein, which has garnered 50 citations and become a valuable tool for researchers worldwide. He also developed a sophisticated cell-based ELISA system designed to identify entry inhibitors that target CXCR4, a key coreceptor exploited by HIV-1 X4 strains during host cell invasion. By engineering both biochemical and cell-based assay platforms, Jiang has substantially accelerated the pace at which potential antiviral compounds can be evaluated, bridging the gap between basic virology and practical drug development. His methodological innovations have provided the research community with reliable, scalable tools essential for identifying the next generation of HIV therapeutics.
Research Focus
Key Achievements
Top Papers
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