Ryma Benayed

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About

Ryma Benayed is a molecular pathologist whose work bridges the gap between cutting-edge genomic technologies and clinical diagnostics. Her primary research focuses on the development and application of novel biomarkers for cancer diagnosis and prognosis, with a particular emphasis on telomerase reverse transcriptase (TERT) expression and its role in tumor biology. In her most-cited study, "Evaluation of TERT mRNA expression using RNAscope®: A potential histopathologic diagnostic and prognostic tool," Benayed demonstrated how RNA in situ hybridization can reliably detect TERT expression in formalin-fixed, paraffin-embedded tissues, offering a practical method for identifying aggressive tumor subtypes. This work, which has garnered 6 citations, underscores her ability to translate complex molecular mechanisms into actionable histopathologic tools. Beyond this, Benayed has contributed to the validation of next-generation sequencing panels for precision oncology, helping to refine how pathologists interpret genetic alterations in solid tumors. Her research is characterized by a meticulous focus on reproducibility and clinical utility, making her a key figure in the evolution of molecular pathology. For students and researchers, Benayed’s work exemplifies how integrating advanced molecular techniques with traditional histology can enhance diagnostic accuracy and guide targeted therapies.